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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
HIBCH
All Species:
33.94
Human Site:
Y330
Identified Species:
53.33
UniProt:
Q6NVY1
Number Species:
14
Phosphosite Substitution
Charge Score:
0.07
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q6NVY1
NP_055177.2
386
43482
Y330
Q
E
V
L
T
M
E
Y
R
L
S
Q
A
C
M
Chimpanzee
Pan troglodytes
XP_515988
440
48807
Y384
Q
E
V
L
T
M
E
Y
R
L
S
Q
A
C
M
Rhesus Macaque
Macaca mulatta
XP_001103467
444
49874
Y388
Q
E
V
L
T
M
E
Y
R
L
S
Q
A
C
M
Dog
Lupus familis
XP_848689
359
39946
G312
L
S
Q
A
C
V
G
G
H
D
F
H
E
G
V
Cat
Felis silvestris
Mouse
Mus musculus
Q8QZS1
385
43019
Y329
Q
E
V
L
I
M
E
Y
R
I
T
Q
A
C
M
Rat
Rattus norvegicus
Q5XIE6
385
43006
Y329
Q
E
V
L
T
M
E
Y
R
L
T
Q
A
C
M
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
Q5ZJ60
385
42810
Y329
Q
D
V
F
T
M
E
Y
R
L
S
Q
A
C
M
Frog
Xenopus laevis
A2VDC2
385
42348
Y329
Q
E
V
L
T
M
E
Y
R
L
S
Q
A
C
M
Zebra Danio
Brachydanio rerio
Q58EB4
382
42258
Y326
Q
E
V
F
M
M
E
Y
R
L
S
Q
A
C
M
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_650453
385
42729
H334
E
Y
R
L
A
V
R
H
L
E
R
S
D
F
K
Honey Bee
Apis mellifera
XP_396249
396
44074
F335
E
F
R
L
M
C
N
F
F
N
K
N
S
D
F
Nematode Worm
Caenorhab. elegans
P34559
288
31153
A241
I
V
Q
M
A
K
E
A
V
N
K
A
Y
E
L
Sea Urchin
Strong. purpuratus
XP_791196
379
41899
Y323
G
N
C
L
S
M
E
Y
R
I
A
E
G
C
I
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q1PEY5
378
42237
D327
R
A
V
L
I
D
K
D
R
N
P
K
W
Q
P
Baker's Yeast
Sacchar. cerevisiae
P28817
500
56270
Q333
T
K
S
P
S
S
L
Q
I
A
L
R
L
V
Q
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
86.8
84.9
84.4
N.A.
81.8
81.6
N.A.
N.A.
69.1
69.6
65.2
N.A.
49.2
47.9
24.6
56.9
Protein Similarity:
100
86.8
86.2
87.8
N.A.
92.2
92.2
N.A.
N.A.
83.9
81.3
78.2
N.A.
67.6
67.1
40.9
75.1
P-Site Identity:
100
100
100
0
N.A.
80
93.3
N.A.
N.A.
86.6
100
86.6
N.A.
6.6
6.6
6.6
40
P-Site Similarity:
100
100
100
13.3
N.A.
93.3
100
N.A.
N.A.
93.3
100
86.6
N.A.
26.6
26.6
20
73.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
39.1
30.2
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
59.8
47
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
20
0
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
40
20
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
7
0
7
14
0
0
7
0
7
7
7
54
0
0
% A
% Cys:
0
0
7
0
7
7
0
0
0
0
0
0
0
60
0
% C
% Asp:
0
7
0
0
0
7
0
7
0
7
0
0
7
7
0
% D
% Glu:
14
47
0
0
0
0
67
0
0
7
0
7
7
7
0
% E
% Phe:
0
7
0
14
0
0
0
7
7
0
7
0
0
7
7
% F
% Gly:
7
0
0
0
0
0
7
7
0
0
0
0
7
7
0
% G
% His:
0
0
0
0
0
0
0
7
7
0
0
7
0
0
0
% H
% Ile:
7
0
0
0
14
0
0
0
7
14
0
0
0
0
7
% I
% Lys:
0
7
0
0
0
7
7
0
0
0
14
7
0
0
7
% K
% Leu:
7
0
0
67
0
0
7
0
7
47
7
0
7
0
7
% L
% Met:
0
0
0
7
14
60
0
0
0
0
0
0
0
0
54
% M
% Asn:
0
7
0
0
0
0
7
0
0
20
0
7
0
0
0
% N
% Pro:
0
0
0
7
0
0
0
0
0
0
7
0
0
0
7
% P
% Gln:
54
0
14
0
0
0
0
7
0
0
0
54
0
7
7
% Q
% Arg:
7
0
14
0
0
0
7
0
67
0
7
7
0
0
0
% R
% Ser:
0
7
7
0
14
7
0
0
0
0
40
7
7
0
0
% S
% Thr:
7
0
0
0
40
0
0
0
0
0
14
0
0
0
0
% T
% Val:
0
7
60
0
0
14
0
0
7
0
0
0
0
7
7
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
7
0
0
% W
% Tyr:
0
7
0
0
0
0
0
60
0
0
0
0
7
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _